The ovarian reserve, estimated by measuring anti-Mullerian hormone (AMH) circulating levels, plays a crucial role in determining the duration and age limit of spontaneous fertility, as well as the efficacy of fertility-promoting treatments: patients with CKD stage 3–5 have lower AMH levels than the general population, although AMH levels in patients on haemodialysis may be high due to impaired glomerular filtration, limiting urinary clearance of the hormone [6]. This evidence concerns the gene AMH and chronic kidney disease.