Past studies have demonstrated that Rab proteins 1, 5, 7, and 11 regulate autophagy14, 15, 16 in the mouse glioma cell line Neuro2A, human glioma cell line SH‐SY5Y, primary cortical neurons, and spinal cord motor neurons, which colocalizes and directly interacts with C9orf72. Here, AGFG1 is linked to central nervous system cancer.