And we sorted CD45+CD19−CD11b−CD3+CD4−PD-1+CD103+CD8+ T cells from the freshly resected INT and TB tissues from the HCC validation cohort (n = 6) for downstream analyses (including 3 HBV+ HCC patients and 3 HBV− HCC patients, Table S3). The gene discussed is CD8A; the disease is hepatocellular carcinoma.