GPT and liver disorder: We collected three HBV serological markers (Hepatitis B surface antigen ‘HBsAg’, Hepatitis B e antigen ‘HBeAg’, Anti-Hepatitis B e antigen ‘Anti-Hbe’), the HBV DNA level, two biochemical parameters (AST/ALT), two noninvasive fibrosis markers (aspartate aminotransferase-to-platelet ratio index ‘APRI’, Fibrosis-4 index ‘FIB-4’), and two histopathological scores (Fibrosis score ‘FS’, Necroinflammatory activity score ‘NAS’), and used these HBV and liver disease clinical markers to represent the grade of necroinflammation and the stage of fibrosis caused by chronic HBV infection [25].