The (TT) dominant model of IFITM3 had odd ratio 0.33, the recessive model (TT + CT) of IFITM3 had no association with the risk of (OR) 0.36, p = 0.04, the CC recessive model odd ratio 2.70 with high association with risk of hepatocellular carcinoma. Here, IFITM3 is linked to hepatocellular carcinoma.