Other identified proteins that differentiated uncomplicated from complicated babesiosis were various complement cascade components (CFI, CFP, C2, SERPING1, C8G), extracellular matrix components (TGFBI), acute phase proteins (ORM1, ITIH2, ITIH4, FGA, TF, RBP4) and lipoproteins (apoE). The gene discussed is TGFBI; the disease is babesiosis.