Except for mesothelioma (MESO) and uveal melanoma (UVM), which lacked normal tissue data, PPP4C transcripts were significantly increased in most (27/31) tumor types and decreased in acute myeloid leukemia (LAML), while no statistical difference was observed in kidney chromophobe (KICH), pheochromocytoma and paraganglioma (PCPG), or sarcoma (SARC) (Fig. S2a). This evidence concerns the gene PPP4C and hereditary pheochromocytoma-paraganglioma.