TP53 and cancer: Reactome pathway enrichment analysis of the epiHSP70 interactors indicated that proteins impacted by epiHSP70s map to key biological processes known to be altered in cancer: mitotic cell cycle, programmed cell death, p53-regulated transcription, DNA-repair, translation, transport, glucose metabolism, signaling as well as immune regulatory pathways (e.g. Interferon signaling, Class I MHC antigen processing) (p-value adjusted FDR < 0.05, Fig. 7c, Supplementary Fig. 19b).