All four mice that received 5 × 106 p18mt tumor cell transplants produced tiny tumors (smaller than 100 mm3 in size) with no metastasis, while during the same time period, all eight mice that received 5 × 106 and 5 × 105 p18mt;Gata3+/− tumor cell transplants developed huge tumors (larger than 1000 mm3 in size) with lung metastasis (Fig. 1C). Here, GATA3 is linked to neoplasm.