Indeed, based on these previous reports, survivin tissue levels may be prognostic for patients with pancreatic cancer.[43,58,63] In addition to these survival data on tissue expression levels of survivin, serum survivin levels have also been associated with poor survival in patients with pancreatic cancer.[43] We found that OS was significantly shorter in patients with high baseline serum survivin levels. Here, BIRC5 is linked to familial pancreatic carcinoma.