In GBM, HOXA1 [12, 13], HOXA2 [13], HOXA3 [13, 14], HOXA5 [15], HOXA6 [14, 16], HOXA7 [16], HOXA9 [16], HOXA10 [17, 18], HOXA11 [19] and HOXA13 [16, 20] were significantly up-regulated, compared to normal tissues. The gene discussed is HOXA5; the disease is glioblastoma.