Given that HSP expression is often regulated by HSF1, we first analyzed the correlation between HSF1 and HSPE1, HSPD1, HSPA9, DNAJB11, DNAJC2, DNAJC7 and DNAJC19 in TCGA-PRAD cohort using the cBioPortal database (Fig. 5C). The gene discussed is HSPD1; the disease is prostate adenocarcinoma.