CD4 and AIDS: In the period of 2003–2012, the TAHOD (TREAT Asia HIV Observational Database) study of 3744 people living with HIV (PLWH) found that 72% of new diagnoses in the Asia-Pacific region were advanced HIV late presenters (with a CD4 count <200 cells/mm3 or an AIDS-defining event within three months of first positive HIV test) [7].