LTF and myocardial infarction: Although Ltf administration did not affect the infarct size and severity of myocardial injury (Figure 2F; Figure S4F-G), treatment with Ltf significantly improved cardiac function and attenuated cardiac remodeling, as presented with significantly higher ejection fraction, fractional shortening and smaller left ventricular dimension post-MI (Figure 2G; Figure S5 andTable S2).