The present study aims to detect the distribution of KLF14 rs4731702 SNP genotypes and evaluate the association of the SNP with serum lipid levels, serum glucose profile, ApoA1, Hb1Ac, total protein, hemoglobin, HOMA-IR levels, etc., in T2DM and cardiometabolic patients. The gene discussed is KLF14; the disease is type 2 diabetes mellitus.