Moreover, considering that FcγR expression were found to be stimulated by IFN-γ in monocytes and macrophages (32–34) and that FcγR markedly affects antigen uptake in macrophages (35), exploring the potential link between FcγR-mediated antibody-dependent infections of M1 macrophages and the surge of cytokine storms caused by SARS-CoV-2 infections also seems logical. The gene discussed is FCGR2A; the disease is infection.