As both an anti-inflammatory and an antioxidant agent, NAC has the effect of inhibiting the release of proinflammatory cytokines such as TNF-α and IL-8, while supplementing exhausted glutathione to exert the free radical scavenging effect, making it as a potential drug of choice for sepsis and acetaminophen-induced poisoning (49–52). The gene discussed is CXCL8; the disease is Sepsis.