We also observed PDHA1, PDHB, FDX1, GLS, DLD, DLAT, LIAS and LIPT1 were down-regulated in ccRCC tumor tissues, while CDKN2A exhibited higher protein expression among tumor samples in CPTAC-ccRCC database (Figure 2D). The gene discussed is DLAT; the disease is nonpapillary renal cell carcinoma.