Furthermore, transcriptomic studies based on The Cancer Genome Atlas (TCGA) database addressed that ccRCC were highly CD8+ T cell infiltrated (only 27% of the tumor showed non-infiltrated features) and presented the highest scores on both the immune infiltration and T cell infiltration among 19 cancer types (23, 24). The gene discussed is CD8A; the disease is nonpapillary renal cell carcinoma.