Fibronectin-rich pre-metastatic organs (lung, liver, testis, spleen, and kidney) are hospitable niches for the recruitment and adhesion of VEGFR1+VLA-4+ BMDCs in murine melanoma and lung cancer models and also in human breast and gastrointestinal cancers, highlighting the clinical relevance of this finding (48). Here, FN1 is linked to melanoma.