RNASET2 and Ventriculomegaly: Consistent with this finding, other laboratories have reported minimal behavioral impairments in uninjured hydrocephalic Sprague-Dawley rats or golden hamsters.10,13 Tu and colleagues found no phenotypical signs of hydrocephalus in uninjured adult male and female Wistar rats, among which 43% had mild ventriculomegaly in MRI.11,24 Also, the 2-year-old R222 RNaseT2 KO hydrocephalus case reported by Ferris and colleagues appeared to have normal sensory behavior, given that it responded normally to foot shock and flashing light and startled to a loud sound.22