FOXM1 and pulmonary fibrosis: In the scenario lung fibroblast activation and silica-induced lung fibrosis, it has been reported that ALKBH5, a demethylase, can demethylate pri-miR-320a-3p to prevent its interaction with DGCR8 and this, in turn, blocks the generation of miR-320a-3p, leading to dysregulation in the expression of its target genes, including forkhead box M1 (FOXM1), which ultimately leads to lung tissue damage [61].