In the context of non-small cell lung cancer, METTL3 has been shown to increase pre-miR-143-3p splicing in an m6A-dependent manner to promote miR-143-3p biogenesis, leading to lung cancer invasion and angiogenesis through a mechanism involving dysregulation of vasohibin 1 (VASH1) expression [62]. The gene discussed is VASH1; the disease is non-small cell lung carcinoma.