GRN and Alzheimer disease: Unlike the associations with the other known AD loci, the interactions of the ULK2 (PG×Age = 7.65 × 10–7), CDK14 (PG×Age = 2.54 × 10–9), PURG (PG×Age = 1.41 × 10–8), LINC02712 (PG×Age = 7.69 × 10–9), and GRN (PG×Age = 1.07 × 10–6) SNPs with age accounted for the significant joint test findings (Table 2).