Up-regulation of PSMD2, PSMD3, PSMD5, and PSMD8 mRNA expression was significantly associated with poor PFS in patients with ovarian serous carcinomas (Fig. 6a, HR = 1.19, 95% CI: 1.02–1.39, P = 0.024; Fig. 6b, HR = 1.19, 95% CI: 1.03–1.38, P = 0.018; Fig. 6d, HR = 1.12, 95% CI: 1.05–1.34, P = 0.012; Fig. 6e, HR = 1.22, 95% CI: 1.04–1.44, P = 0.016), while down-regulation of PSMD12 and PSMD14 mRNA expression was associated with poor PFS (Fig. 6g, HR = 0.84, 95% CI: 0.71–0.98, P = 0.032; Fig. 6h, HR = 0.82, 95% CI: 0.71–0.95, P = 0.0085). Here, PSMD12 is linked to ovarian serous carcinoma.