SMG7 and neoplasm: The Tam treated group had an average tumor mass that was ~ 63% lower than the average tumor mass of the CO treated group (CO 0.1998 g ± 0.0382 & Tam 0.0725 g ± 0.0178; P = 0.0023) (see Fig. 4i,j), giving credence to the possibility of targeting SMG7 function for STS treatment.