The mGPS is an inflammatory score that correlates with sarcopenia7 and tumor cachexia.16 The term laboratory cachexia has been defined similarly to mGPS as a CRP level greater than 10 mg/L and coinciding albumin less than 35 g/L by Gray et al.17 Of note, the prevalence of laboratory cachexia increases markedly up to 85% 0 to 30 days before death.17 These data underscore the high mortality in patients with a high-risk mGPS constellation and laboratory cachexia and suggest that the mGPS is capable of measuring not only tumor dynamics but also the patient’s inflammatory and metabolic status. The gene discussed is ALB; the disease is Cachexia.