The results demonstrated that the eosinophil count (p = 0.0067, Figure 2A), CD8+T cell count (p = 0.0126, Figure 2B), CD8+CD38+T cell count (p = 0.0419, Figure 2C), and ELR (p = 0.0159, Figure 2D) were significantly higher in patients with PR than in those with non-PR in the ESCC cohort. This evidence concerns the gene CD8A and esophageal squamous cell carcinoma.