In the ROC analysis, the areas under the curve (AUCs) for discriminating the ESCC cohort patients with PR from those with non-PR according to the eosinophil count, CD8+T, memory CD4+T cell count, and ELR were 0.797 (p = 0.007), 0.775 (p = 0.012), 0.749 (p=0.022), and 0.757 (p = 0.018), respectively (Figure S5 A-D). The gene discussed is CD4; the disease is esophageal squamous cell carcinoma.