Hemoglobin (Hb, Figure 3A), eosinophils (Figure 3B), CD4+CD28+T/CD4+T percentage (Figure 3C), CD8+CD38+T/CD8+T percentage (Figure 3D), memory CD4+T (Figure 3E), and CD4+CD28+T (Figure 3F) were all identified as predictors for distinguishing patients with non-PD from those with PD in the ESCC cohort. This evidence concerns the gene CD28 and esophageal squamous cell carcinoma.