CTLA4 and neoplasm: For vaccination, 2×106 Myc inhibitor (BET/JQ1) treated and irradiated (40 Gy) Neuro2a cells were injected (subcutaneously) into the left flank of each mouse on day 7, 10 and 13 as a whole tumor cell vaccine along with anti-CTLA-4 and anti-PD-L1 antibodies (100 μg/mouse) administered intraperitoneally.