Nanostring analysis revealed that the heart, kidney and lung from the vaccination group demonstrated a moderate to severe level of upregulation in the expression of signature markers for total TIL, CD45 cells, T cells, CD8+ cells, NK cells, dendritic cells, neutrophils, macrophages, and B cells when compared with naïve and tumor only control mice (Figure 1B; Supplement Figure 1). This evidence concerns the gene CD8A and neoplasm.