FGF19 and colorectal carcinoma: To further validate the clinical relevance of FGF19 expression, we analyzed a cohort of 122 human CRC tissues via immunohistochemical (IHC) staining of FGF19 and found that FGF19 expression was higher in CRC than that in normal tissues and higher in LM(+) CRC than that in LM(−) CRC tissues, consistent with previous results (Figure 1D,E).