EEIG1 and glaucoma: Finally, recent reports have implicated FAM102A variants in glaucoma (Khor et al., 2016; Li et al., 2020; Nongpiur et al., 2018; Shi et al., 2021; Zhuang et al., 2018), an eye disorder linked to altered ECM components and abnormal ECM histology (Hernandez and Ye, 1993; Nikhalashree et al., 2019; O'Callaghan et al., 2017; Tribble et al., 2018; Vranka et al., 2015; Wiggs, 2015).