Examples of the potential use of the MAL-family members as cancer biomarkers in these types of test are MAL methylation assays in blood-derived samples from patients with COAD-READ [169], BRCA [170,171], and CESC [172], and in urine and feces from BLCA [89,90] and COAD-READ [173] patients, respectively; and analysis of MAL2 transcript levels in blood from gynecological and metastatic breast cancer patients [174,175]. The gene discussed is MAL; the disease is cancer.