Other examples of dramatic differences in gene expression are the downmodulation of MAL in HNSC (250-fold), and its upregulation in OV (30-fold) and THYM (70-fold); MAL2 upregulation in BRCA (7-fold), CESC (485-fold), COAD (28-fold), OV (750-fold), PAAD (10-fold), READ (almost 90-fold), and UCEC (350-fold); MALL upregulation in STAD (almost 10-fold); PLLP downmodulation in SARC (10-fold) and SCKM (44-fold downmodulated); and MYADM upregulation in PAAD (10-fold) (Figure 4 and Table S1). This evidence concerns the gene MALL and pancreatic adenocarcinoma.