MAL2 is upregulated in multiple human cancers relative to normal tissues and in cancer-derived cell lines, including BRCA [95,96,97], pancreatic adenocarcinoma (PAAD) [98,99,100], HNSC [101], COAD-READ [102], ovarian cancer (OV), STAD [103,104,105], uterine corpus endometrial cancer (UCEC) [103,104], mesothelioma [106] and neuroblastoma [107]. This evidence concerns the gene MAL2 and pancreatic adenocarcinoma.