We analyzed the protein expression of MYC and YBX1 by immunohistochemistry in a tissue microarray of tissue cores from 32 RMS patients, including 17 primary tumors (12 FN and 5 FP) and 15 recurrent or metastatic tumors (8 FN and 7 FP) along with 5 muscle controls. This evidence concerns the gene YBX1 and metastatic neoplasm.