HSD17B6, hydroxysteroid 17-beta dehydrogenase 6, is involved in androgen catabolism and has been implicated in polycystic ovarian syndrome (PCOS) [47], including metabolic perturbations correlated with PCOS, including increased BMI, fasting insulin, and insulin resistance [48]. The gene discussed is HSD17B6; the disease is polycystic ovary syndrome.