To further investigate the mechanisms of differentiated tumour cell exit from postchemotherapy shock, we isolated two tumour cell lines, which, according to our data, have different levels of ectopic WNT signalling activation: T47D with high levels of WNT signalling activation (FZD9-Gain +1, TSF7L2-Loss +1, CCND1-Gain +1, CSNK2A2-Loss +1, FZD2-Gain +1, WNT3-Gain +1, WNT9B-Gain +1, for a total of 7) and BT-474 line with normal WNT signalling (GSK3B-Gain -1, FZD9-Gain +1, TSF7L2-Gain -1, CCND1-Gain +1, total 0) (Table 1). This evidence concerns the gene FZD2 and neoplasm.