The claudin-low/non-ER-negative/HER2-negative group had a higher prevalence than claudin-low/ER-negative/HER2-negative cancers of amplifications in loci 11q13.3, 17q12 and 8p11.23, encoding for the genes CCND1, ERBB2 and NSD3, respectively (Table 5). This evidence concerns the gene NSD3 and cancer.