Experimentally, inactivation of SMARCA4 potentiates lung adenocarcinoma and its metastasis [11,12], while displacement of SMARCB1 (BAF47), another key component of SWI/SNF complex, from SWI/SNF complex by SSX-SS18 fusion protein is associated with oncogenesis of synovial sarcoma [13]. This evidence concerns the gene SMARCA1 and synovial sarcoma.