TFRC and type 2 diabetes mellitus: Professor José Manuel Fernández-Real [21] found that the frequency of the G allele at the position 210 of the TFRC gene was significantly higher in patients with T2DM and sixteen other TFRC SNPs were also associated to T2DM according to the Welcome Trust Case Control Consortium data, demonstrating that TFRC gene polymorphisms are associated with T2DM.