Based on the fact that M1-21 inhibited both FOXM1 expression and function, we observed that M1-21 inhibited a range of cancer types in addition to breast cancer, such as lung adenocarcinoma, colon cancer, renal clear cell tumor, cervical cancer, bladder cancer, and glioma U251, in cell culture (see above). The gene discussed is FOXM1; the disease is malignant colon neoplasm.