FN1 and keloid: However, related to the keloid phenotype, the increase in fibronectin observed after cortisol treatment in our experiments is contradictory to that of the decreased collagen expression, as keloid fibroblasts show increased excretion of collagen type I. Therefore, our findings further support the notion of distinct mechanisms underlying upregulation of fibronectin expression in fibroblasts as described in Babu et al.42.