The focal adhesion kinase (FAK) is a key regulator of the focal adhesion pathway, which was evidently enriched in the KEGG analysis of DEGs described previously, and its signal cascade, the FAK/AKT pathway, is involved in the development of cardiac hypertrophy by regulating various cellular responses.[31, 32] We then investigated whether the FAK/AKT pathway is involved in FBLN7‐driven fibroblast activation during cardiac remodeling after MI. The gene discussed is FBLN7; the disease is cardiac hypertrophy.