Although the present study has confirmed that NEAT1 and IL-6 are differently expressed in SLE and that NEAT1 targets IL-6, it should be noted that potential additional clinical correlations between NEAT1 and SLE need to be investigated, as well as the relationship of SLEDAI scores with NEAT1 and IL-6 secretion. This evidence concerns the gene NEAT1 and systemic lupus erythematosus.