However, other studies have shown the presence of smaller protein fragments in various models, including NF-L (Posmantur et al., 1994) and MBP in models of traumatic brain injury and neurodegenerative autoimmunity (Liu et al., 2006; Belogurov et al., 2015), as well collagen IV (McColl et al., 2008) and laminin (Zalewska et al., 2003) in models of cerebral ischemia. This evidence concerns the gene MBP and brain ischemia.