Intracardiac thrombi are associated with the same principle of thrombogenesis as anywhere else in the body, i.e., Virchow's triad; (a) stasis [dys- or hypokinesis as in CM, myocardial stunning as in MI], (b) hypercoagulability (e.g., post-MI inflammation, factor V Leiden and acute myeloid leukemia), and (c) endocardial injury (post-MI, eosinophilic myocarditis, etc.)[3]. Here, F5 is linked to acute myeloid leukemia.