Molecular, as well as docking studies, confirmed that kaempferol work on resistant cancer cells by inhibiting mTOR, TGF-beta and P-gp and our team proposed that kaempferol can be validated as a potent yet safe mTOR inhibitor.16,17 As of 2013, approximately, there are more than six hundred published in vitro studies and around two hundred in vivo reports on the chemo sensitizing potential of phenolic compounds, which is significantly more than its reports for chemo preventive and chemotherapeutic effect.18 The gene discussed is MTOR; the disease is cancer.