The presence of antihypertensive action of OVP-1 on models of acute and sustained arterial hypertension has been experimentally proved.11 Because the antihypertensive activity of OVP-1 may be related to its effect on the synthesis of vasodilating factor cGMP, the effect of the oxazole derivative on the change in the activity of its regulator, the PDE enzyme, was investigated. Here, ALDH7A1 is linked to Hypertension.