CD8A and hyperplasia: Non-infectious CVID enteropathy according to biopsy-proven villous atrophy, increased intraepithelial lymphocytosis (IEL), absence of plasma cells and/or follicular lymphoid hyperplasia, increased frequency of CD8+ T cell infiltrates in the intestinal lamina propria, or as inflammatory bowel disease was present in 45% of patients with liver involvement, compared with 29% without (p=ns).