TGFB1 and breast cancer: Remarkably, CD73+ γδ1 Treg cells exhibit high expression of IL-4, IL-10, IL-17A, GM-CSF, and TGFβ, which are critical immunosuppressive molecules, indicating that CD73+ γδ1 Treg cells have an immunosuppressive role in the TIME of BC (105) (Figure 3).