FGFR1 and osteoglophonic dysplasia: A number of diseases with impaired FGF-23 regulation have been described, such as osteoglophonic dysplasia, where fibroblast growth factor receptor 1 (FGFR1)-activating mutation leads to increased FGF-23 production or familial tumoral calcinosis, where a mutation limiting the cleavage of FGF-23 leads to ectopic calcifications [28].