Xiong et al. (2020) proved that the conditional deletion of RCOR1 in Foxp3+ Tregs had waken the function of Tregs, while the proportion of IL-2 and IFN-γraised up in peripheral lymphoid tissues and promoted antitumor immunity. In our study, expression of RCORs correlated to the infiltration of congenital and specific immune cells in HCC. Given that, it’s worthwhile to detect the tumorous immune characteristics of RCOR genes. This evidence concerns the gene RCOR1 and hepatocellular carcinoma.