Of the adenocarcinoma-mimicking lesions of the prostate gland, granulomatous prostatitis (GP) usually has the same clinical appearance as PCa, with obstructive and/or irritative symptoms, a diffuse or focal enlargement of the gland at digital rectal examination, and increasing levels of prostate-specific antigen (PSA) (4). The gene discussed is KLK3; the disease is adenocarcinoma.