There was no evidence of association for specific segmentations of the retina, including the retinal nerve fiber layer (β = −0.12, SE = 0.79, P = 0.13) (Fig. 2b), ganglion cell–inner plexiform layer (β = −4.4 × 10−3, SE = 0.10, P = 0.97), and, most important, the RPE (β = 0.097, SE = 0.15, P = 0.51) (Fig. 2c) and the photoreceptor layer (β = −0.017, SE = 0.049, P = 0.72) (Fig. 2d), which are the retinal layers most affected in ABCA4 retinopathy. This evidence concerns the gene ABCA4 and retinal disorder.